منابع مشابه
Off-targeting oft-targeted CD20 in cHL.
We now think of classical Hodgkin lymphoma (cHL) as derived from "crippled" germinal center B cells that have frequently acquired rearranged and somatically mutated Ig genes.1,2 Despite their B-cell origin, the malignant Hodgkin and Reed-Sternberg (HRS) cells have lost most of the superficial trappings of B cells and therefore have been hidden from investigators' lenses for decades, prompting a...
متن کاملReview Study: Intravenous Thrombolysis, Time Window, Dosage, and Off-Label
Despite the development of Intravenous thrombolysis with tissue Plasminogen Activator (IVtPA) guidelines in each affiliated stroke center, protocol violations may be observed in each hospital with IVtPA facilities. An extensive search of scientific electronic databases including PubMed, OVID, Index Medicus, Index Copernicus, Google, ISI, and Scopus was performed with keywords of Thrombolysis, O...
متن کاملOff-Label Drug Information
drug into interstate commerce unless the FDA has approved the drug and its label.2 A second provision prohibits manufacturers from introducing misbrandeddrugs into interstate commerce.2 Misbranding is considered to occur if drug labeling contains information that describes unapproved uses or is misleading or insufficient to support safe use for approved indications.2 Materials are considered pa...
متن کاملOff-label antibiotic preparation.
Dear Editor: Sterile ophthalmic injections with 2 antibiotics (ceftazidime and vancomycin) and 1 glucocorticoid (dexamethasone) are used at University Hospital of Geneva in some patients with infectious complications after intraocular surgeries. This is an off-label indication. They are administered as intravitre-ous injections and need to be prepared just before utilization , because the subst...
متن کاملOff-label use of vaccines.
This article reviews the off-label recommendations and use of vaccines, and focuses on the differences between the labelled instructions on how to use the vaccine as approved by the regulatory authorities (or "label"1), and the recommendations for use issued by public health advisory bodies at national and international levels. Differences between public health recommendations and the product l...
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ژورنال
عنوان ژورنال: InFo Neurologie & Psychiatrie
سال: 2012
ISSN: 1437-062X
DOI: 10.1007/s15005-012-0048-4